By Nasuhi Engin AydinAntimicrobial agent ornidazole yields promising effects in an animal model of endometriosis
By Nasuhi Engin Aydin
Xiaoduo Qin and collaborators from Chinese medical centers, have published their results on the role of ornidazole using an experimental rat model in a recent issue of the periodical “Gynecologic and Obstetric Investigation”. Progression of endometriotic foci depends on the presence…
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Atherosclerosis is augmented in laboratory mice by experimental endometriosis
By Nasuhi Engin Aydin
Dr. Taylor group from Yale School of Medicine, New Haven, CT, USA has published their experimental study in the "American Journal of Obstetrics & Gynecology" on atherosclerosis following endometriosis induction in laboratory mice. The basic inflammation process in endometriosis patients…
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Immunotherapy in endometriosis: a challenging research topic
By Nasuhi Engin Aydin
Dr. Maksym and associates from academic centers in Poland have published their comprehensive review on endometriosis emphasizing the immunological aspects of the disease in a recent issue of the "Journal of Clinical Medicine". Even though endometriosis is a multifactorial disease,…
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By Bahar YukselShining like fireflies: a new approach to visualize early endometriosis
By Bahar Yuksel
Endometriosis is a complex and unsolved disease that requires animal studies in order to understand its nature. There are a group of animal models designed for endometriosis studies, but most require sacrificing the animal. In the experimental study designed by the team…
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New molecular insights in endometriosis pathogenesis
By Nasuhi Engin Aydin
Dr. Rosalba Siracusa and associates from Messina University, Italy, have published their research on cellular pathogenesis of experimental endometriotic lesions in the recent issue of the "International Journal of Molecular Sciences". Endometriosis is a debilitating chronic estrogen-dependent inflammatory condition and…
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Natural history of spontaneous endometriosis in crab-eating monkeys
By Nasuhi Engin Aydin
Kaori Hayashi and associates from Shiga University of Medical Science, Japan, published their observations on spontaneously occurring endometriosis in crab-eating monkeys in "Tohoku Journal of Experimental Medicine"https://www.jstage.jst.go.jp/article/tjem/251/4/251_241/_pdf/-char/en. The presence of endometrial tissue outside the uterus, i.e., endometriosis is a progressive prevalent…
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By Yu YuAnimal models of endometriosis
By Yu Yu
For advancing understanding and treatment of endometriosis, The World Endometriosis Society has previously brought together researchers and clinicians to discuss the many important research priorities. One of these was the recommendation to development and building on the use of animal…
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By Özge ÖzkayaTFF3 May Be Involved in Endometriosis Research Suggests
By Özge Özkaya
Levels of a protein called TFF3 are significantly increased in the peritoneal cavity (the abdominal space) of women with endometriosis, found a study published in the scientific journal Reproductive Sciences. This increase was in line with levels of other known…
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A Cholesterol-Lowering Drug and an Anticancer Drug May Be Alternative Treatments Against Endometriosis
By Özge Özkaya
Crestor (rosuvastatin), a cholesterol lowering drug and Avastin (bevacizumab), an anticancer drug are more efficient in reducing endometriosis in rats compared to progesterone medication, according to a study published in the journal Gynecological Endocrinology. For the study, researchers led by…
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Endometriosis Micrometastasis
By Yu Yu
Micrometastasis is used to describe the migration of a small number of cancer cells from its original location to the other organs within the body. While endometriosis is not cancer, it occurs when endometrial cells migrate outside of the uterus…
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